Creation, Evaluation and Application of an Integrated Environmental Fate And Human Food chain Bioaccumulation Model for Polar and Non-Polar Organic Substances
Person photo Prof Michael McLachlan
Analytical Environmental Chemistry (Department of Applied Environmental Science)

Funding source: Cefic European Chemical Industry Council
Period: 10/1/06 - 9/30/09
Funding: 274950 EUR
Description:
The work content is structured according to the project objectives listed above. 1. To create a mechanistically based, non-steady state, chemical fate and bioaccumulation model to predict wildlife and human exposure to organic chemicals. 2. To further develop this model to make it applicable to polar chemicals that engage in hydrogen bonding. 3. To evaluate the utility of the model and demonstrate its range of applicability. 4. To explore how physical chemical properties, and most particularly those properties determining persistence in the physical environment and food chain, affect human and wildlife exposure, and to evaluate this information in the context of current regulatory definitions of PBT chemicals. 5. To evaluate the influence of environmental properties and factors on chemical uptake and accumulation in wildlife and humans. 6. To evaluate what combination of emissions scenario and physical chemical properties makes it necessary to use a non-steady state (as opposed to a steady state) model. 7. To ascertain the utility of the integrated model in higher tier assessments within the current European risk assessment framework.
  
Partner Org. (3)
Research fields (1)
  
Swiss Federal Institute for Environmental Science and Technology
, Switzerland
University of Oslo
, Norway
University of Toronto
, Canada