Developmental Biology (Wenner-Gren Institute)
Head of unit:  Dr Olga Shilkova
Phone: +468162000
Fax: +4686126127
Website: http://www.wgi.su.se
Address:  
Arrheniuslab E 3, Svante Arrheniusväg 16 - 18
10691 Stockholm
Sweden

  
Contracts (16)
Researchers (4)
 
A molecular genetic approach to study mating type switch, DNA double strand break repair and chromatin in yeast
Period: 1/1/08 - 12/31/10
Mating type switch in the yeast K. lactis is uncharacterized. We identified two proteins, Mts1 and Alpha3, necessary for switching. Overexpression of Mts1 induces switching and transcription of MTS1 itself is regulated by nutrients and cell-type. Alpha3 shares similarity with plant transposases, ...
Functions of the Atrophin-Brakeless protein complex in neurodegeneration and gene regulation
Period: 1/1/09 - 12/31/11
The aim of this research is to characterize the gene regulatory properties of Atrophin-1, the causative agent of the neurodegenerative disease dentatorubral-pallidoluysian atrophy, and its interaction partner Brakeless, with the goal of understanding and treating the gene expression changes that ...
Investigation of the anti-cancer molecule Endostatin function at a molecular level using Drosophila as a model organism
Period: 1/1/09 - 12/31/09
Funktionen och mekanismen av anti-cancer molekylen Endostatin i en intakt organism: en samordnad studie i funktionell genetik. Kroppens celler behöver syre och näring för att fungera och det tillförs via blodkärl som bildas under fosterutvecklingen. Även senare i livet bildas nya blodkärl tex vid ...
Molecular dissection of airway maturation in Drosophila
Period: 1/1/10 - 12/31/12
Oxygen is vital for aerobic respiration and many animals evolved elaborate organs for its efficient transport and delivery to all cells in the body. Like our lungs and blood vessels, the tracheal airways deliver oxygen to all tissues of Drosophila and provide an excellent model system for the ...
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