Prof Mattias Mannervik
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Contracts (3)
 
Functions of the Atrophin-Brakeless protein complex in neurodegeneration and gene regulation
Period: 1/1/09 - 12/31/11
The aim of this research is to characterize the gene regulatory properties of Atrophin-1, the causative agent of the neurodegenerative disease dentatorubral-pallidoluysian atrophy, and its interaction partner Brakeless, with the goal of understanding and treating the gene expression changes that ...
Transcriptional regulation in Drosophila development
Period: 1/1/09 - 12/31/11
The goal of this research is to understand the molecular mechanisms of gene control that are used in animal development. We have previously identified two novel transcriptional co-repressors required for Drosophila development. One of them, Brakeless, interacts with the causative agent of a ...