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Developmental Biology (Wenner-Gren Institute)
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Epigenetik och kromatinreglerande proteiner i Drosophila
Functions of the Atrophin-Brakeless protein complex in neurodegeneration and gene regulation
The aim of this research is to characterize the gene regulatory properties of Atrophin-1, the causative agent of the neurodegenerative disease dentatorubral-pallidoluysian atrophy, and its interaction partner Brakeless, with the goal of understanding and treating the gene expression changes that ...
Transcriptional regulation in Drosophila development
The goal of this research is to understand the molecular mechanisms of gene control that are used in animal development. We have previously identified two novel transcriptional co-repressors required for Drosophila development. One of them, Brakeless, interacts with the causative agent of a ...
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