Prof Barbara Cannon
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Contracts (4)
RSS 2
ATOM
 
Adipokines as Drug Targets to Combat Adverse Effects of Excess Adipose Tissue
Period: 2/1/08 - 1/31/12
Obesity represents the major risk factor for the cardiometabolic syndrome, which is an epidemic disease that generates a severe global socio-economic burden for the public health systems. Enhanced production of proinflammatory adipocytokines by expanded adipose tissue is now considered as a key ...
Brown adipose tissue and human obesity
Period: 1/1/10 - 12/31/10
Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes
Period: 10/1/11 - 9/30/15
The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and ...
The physiology of thermogenesis: acute and adaptive processes in brown adipose tissue
Period: 1/1/08 - 12/31/10
Brown adipose tissue is an organ unique to mammals, and is responsible for nonshivering thermogenesis. Central to an understanding of thermogenesis is an understanding of the mitochondrial uncoupling protein UCP1; regulation of its activity will be examined in-vitro and in knock-in mice with ...